Kev tshawb fawb ntau lub chaw tsis ntev los no ntawm kev kuaj mob ntawm cryptococcal kab mob tau ua los ntawm Lub Chaw Kho Mob ntawm Utrecht University, Lub Tsev Kawm Ntawv ntawm Biodiversity thiab Ecosystem Dynamics ntawm University of Amsterdam, Westerdijk Lub Tsev Haujlwm rau Fungal Biodiversity, thiab Matogro Lub Fungi Research Laboratory ntawm lub Tsoom Fwv Teb Chaws University of Somalia thiab Júlio Muller University Tsev Kho Mob ntawm Tsoom Fwv Tsev Kawm Ntawv Qib Siab Mato Grosso tau sib koom ua ke thiab luam tawm lub npe "Kev tsis saib xyuas cov noob caj noob ces" hauv phau ntawv Journal of Clinical Microbiology thaum Lub Ib Hlis 2021. Ntau haiv neeg cuam tshuam kev kuaj mob raws sij hawm ntawm Cryptococcus kab mob” tsab xov xwm.Tsab ntawv xov xwm no sib piv plaub cryptococcal colloidal kub kuaj cov khoom, thiab ntsuas qhov kev kuaj mob ntawm txhua yam khoom rau cov kab mob cryptococcal sib txawv los ntawm kev xaav ntawm ntau haiv neeg ntawm Cryptococcus neoformans thiab Cryptococcus guttata.Muab lub hauv paus zoo rau kev kuaj mob sai ntawm Cryptococcus.
Plaub lub npe ntawm cryptococcal colloidal kub ceev kuaj reagents tau siv los kuaj cov kab sib txawv uas cuam tshuam txog cov caj ces ntawm cryptococcus, suav nrog cov khoom ntawm plaub lub tuam txhab thiab cov npe suav nrog Tianjin FungiXpert® thiab IMMY Diagnostics ntawm Tebchaws Meskas.Plaub caug hom kab mob Cryptococcus suav nrog tag nrho xya hom kev lees paub thiab lawv cov hybrids interspecific tau sim.
Cov txiaj ntsig tshawb fawb:
Cov txiaj ntsig kev tshawb fawb pom tau tias FungiXpert® (Genobio's brand) thiab IMMY's colloidal kub kuaj daim npav tuaj yeem ntes tag nrho xya tus kab mob Cryptococcus.
Thaum kuaj lwm ob cov khoom kub colloidal, qee hom kab mob xws li C. bacillisporus, C. deuterogattii, thiab C. tetragattii, tshwj xeeb tshaj yog C. tetragattii, yog qhov ua rau cov txiaj ntsig tsis zoo.Txawm li cas los xij, tus kab mob C. tetragattii muaj tshwm sim hauv sub-Saharan Africa thiab Indian subcontinent, uas muaj cov neeg mob HIV ntau tshaj plaws ntawm cryptococcal meningitis.Qhov tseem ceeb, 13-20% ntawm cov kab mob HIV cuam tshuam nrog cryptococcal meningitis muaj feem xyuam rau C. tetragattii.
Raws li cov ntaub ntawv tsis ntev los no ntawm cov txiaj ntsig tsis zoo hauv kev sim cryptococcal hauv Botswana thiab Uganda, cov kws sau ntawv tau xaus lus tias C. tetragattii yuav muaj nyob rau hauv cov qauv tshawb fawb soj ntsuam nrog cov txiaj ntsig tsis zoo no.
Analysis xaus:
Tus kws sau ntawv qhia tias nyob rau hauv kev tsim los yog kev ntsuam xyuas ntawm cryptococcal nrhiav kom tau txoj kev, cov kab mob hauv zos, keeb kwm ntawm caj ces thiab ntau haiv neeg taxonomic yuav tsum raug txiav txim siab.Pathogenic Cryptococcus yuav tsum tsis txhob txwv rau ib qho kev faib tawm ntawm AD serotypes.Xav txog cov kev hloov kho cryptococcal kev faib tawm hauv cov khoom tsim thiab kev txheeb xyuas tuaj yeem txo qhov rhiab heev los ntawm qhov tsis zoo tsis tseeb.
Lub cryptococcal capsular polysaccharide nrhiav pom daim npav (colloidal kub txoj kev) tsim thiab tsim los ntawm Genobio Pharmaceutical Co., Ltd. txais yuav txoj kev kuaj xyuas colloidal kub, uas tuaj yeem txheeb xyuas txhua hom cryptococcal hom.Kev ua haujlwm yog yooj yim, thiab cov txiaj ntsig yog intuitive thiab siv tau.Tom qab pom cov txiaj ntsig Kev Xeem tuaj yeem tau txais hauv 10 feeb!Muab lub hauv paus txhim khu kev qha ntau dua rau kev kuaj mob sai thiab sai ntawm Cryptococcus!
Tsab ntawv Source:
Shi D, Haas PJ, Boekhout T, et al.Kev tsis saib xyuas kev sib txawv ntawm caj ces cuam tshuam kev kuaj mob raws sij hawm ntawm Cryptococcus kab mob [J].Phau ntawv Journal of Clinical Microbiology, 2021.
Kab lus txuas:
https://journals.asm.org/doi/10.1128/JCM.02837-20
Post lub sij hawm: Lub Xya hli ntuj-28-2021